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Astragaloside IV (AIV) 1% – Telomere Activator, DNA Repair


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Astragaloside IV is a triterpenoid saponin with potential anti-aging properties. The substance works by stimulating the repair of DNA damage by activating telomerase, which is a nucleoprotein enzyme that catalyses synthesis and growth of telomeric DNA.

EAN: 0793869836711 SKU: 10005977 Categories: , ,


Astragaloside IV 1% Powder (AS-IV) is an cycloartane-type triterpene compound found in minute amounts in the astragalus root. The substance is believed to stimulate the repair of DNA damage through activating telomerase, which is a nucleoprotein enzyme which catalyses synthesis and growth of telomeric DNA.

Telomeres in turn are made of thin filaments and are found at the tips of chromosomes. Maintaining their stability enables cells to avoid replicative senescence and indefinite proliferation beyond the Hayflick limit. Telomeres shorten with each cycle of cell division, or when subjected to oxidative stress. Until today, this has been an unavoidable mechanism of aging.

Astragaloside IV is also used as an immunostimulant because of its ability to increase T-lymphocyte proliferation. T-cells plays a role by killing infected host cells, in producing cytokines, and by activating the other immune cells. Finally, has a similar chemical structure to that of the cycloastragenol (CAG) molecule, but a higher dose needs to be taken to achieve the same effect. Because astragaloside IV is considerably less pricey than cycloastragenol, it is a great alternative to CAG.

Immune System

Astragaloside IV is celebrated for its immunomodulatory properties, which help strengthen and balance the immune system. It enhances the activity of immune cells, such as T cells, B cells, and natural killer (NK) cells, promoting overall immune function. This immune-supporting effect makes it valuable for bolstering the body’s defenses against infections and diseases.


The extract exhibits potent anti-inflammatory properties by inhibiting the production of pro-inflammatory molecules and cytokines. It helps reduce inflammation throughout the body, which can alleviate symptoms associated with inflammatory conditions. There is some evidence that shows that Astragaloside IV can increase the production of white blood cells, which could help to fight off infections and illness.


Studies suggest that it may benefit cardiovascular health by improving various risk factors for heart disease. It helps lower blood pressure, reduce cholesterol levels, and prevent the formation of arterial plaques, thereby lowering the risk of atherosclerosis, heart attacks, and strokes. Additionally, it supports overall heart function and may protect against cardiac remodeling.


Astragaloside IV exhibits potent antioxidant properties, scavenging free radicals and preventing oxidative damage to cells and tissues. By neutralizing oxidative stress, it helps protect against age-related degenerative diseases, including neurodegenerative disorders like Alzheimer’s and Parkinson’s disease, as well as cancer.


The supplement may offer neuroprotective benefits by enhancing cognitive function, protecting neurons from damage, and promoting nerve cell regeneration. It has shown promise in improving memory, learning, and focus, making it a potential therapeutic agent for neurodegenerative conditions like Alzheimer’s disease.


Astragaloside IV has been touted for its anti-aging effects, attributed to its ability to combat oxidative stress, inflammation, and cellular damage. By supporting cellular health and vitality, it may slow down the aging process, improve skin elasticity, and promote longevity.

Skin Health and Wound Healing

Astragaloside IV promotes wound healing and skin regeneration by enhancing collagen synthesis, promoting tissue repair, and accelerating the closure of wounds. It also possesses anti-inflammatory and antimicrobial properties, which can help prevent infections and reduce skin irritation.


The astragalus compound has hepatoprotective effects, meaning it helps protect the liver from damage caused by toxins, medications, or chronic diseases. It supports liver function, aids in the detoxification process, and may mitigate liver inflammation and fibrosis.


Astragaloside IV may have adaptogenic properties, helping the body adapt to stress and maintain homeostasis. By modulating the stress response and supporting adrenal gland function, it may alleviate symptoms of stress, anxiety, and fatigue.

Suggested use

The suggested dose is between 50 mg and 400 mg daily for adults.


Astragaloside IV (AIV) 1%. Extracted from the root of Astragalus membranaceus.


The various effects are not guaranteed and results may vary due to several factors between different people.

We strive to ensure the accuracy of the information provided by the manufacturers and recommend that you read all labels and warnings. However, the information is not a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment.

Astragaloside IV (AIV) 1%
Astragaloside IV (AIV) 1%
Weight (Bag)

1000g (35.3oz), 100g (3.5oz), 200g (7.1oz), 500g (17.6oz)


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