, , ,

Organic Shiitake Mushroom Extract – Immunity, Cytokines, Beta-Glucans


+ Minimal Shipping

Shiitake mushroom extract is made from the species of Lentinula edodes. The compounds may activate the immune system and the production of cytokines.


Organic Shiitake Mushroom Extract with AHCC is a fungi powder that offers a spectrum of health advantages. A long-line of clinical studies have found that shiitake activates the immune system by enhancing the production of cytokines, which are the well-known immune-signaling molecules. The cytokines also increases the activity of particular white blood cells, including natural killer (NK) cells, dendritic cells (DC), T cells, and macrophages. This is part of the immune system’s coordinated response to pathogens and abnormal cells.

The activation of cytokines is associated with the carbohydrate-related molecules called glucans. In the organic shiitake mushroom extract they are found in an unusual large amount and in a form called beta glucans. These glucans are not broken down by enzymes in the digestive tract, which means they traverse through to the large intestine were they support the bacteria flora.

These polysaccharides also functions as free radical scavengers that improve the regulation of blood sugar levels. Aside from the beta glucans, we also find other prebiotic digestive enzymes in shiitake, along with amino acids, proteins, peptides, selenium, and antioxidants, such as glutathione, ergothioneine, polyphenols, flavonoids, SOD (superoxide dismutase).

Immune System

Shiitake mushrooms are renowned for their immune-boosting properties, and AHCC, a compound derived from shiitake, further amplifies this effect. The supplement promotes the activity of immune cells, enhancing the body’s defense mechanisms against infections and illnesses.

Antiviral and Antimicrobial

The mushroom may exhibit potent antiviral and antimicrobial effects. Research suggests that these compounds may help combat various pathogens, offering a natural defense against viral infections and microbial threats.


Shiitake mushroom extract exhibits anti-inflammatory properties, potentially helping to alleviate chronic inflammation. Chronic inflammation is implicated in various health conditions, and the supplement’s anti-inflammatory effects contribute to overall well-being.


The fungi possess antioxidative properties, shielding cells from oxidative stress. This protection against free radicals may reduce cellular damage, supporting longevity and mitigating the risk of chronic diseases associated with oxidative damage.


Shiitake mushrooms are believed to support liver health. Supplementation may aid in liver function, promoting detoxification processes and potentially reducing the risk of liver-related disorders.


Components in the mushrooms, including beta-glucans, have demonstrated positive effects on heart health, e.g. by maintaining healthy cholesterol levels.


Shiitake mushrooms are recognized for their positive impact on the digestive system. The supplement may contribute to gastrointestinal health by promoting the balance of gut microbiota and supporting digestive functions.

Potentially Anti-Cancer

The AHCC, derived from shiitake, has shown promise in the prevention and as a supportive therapy. Studies indicate its potential to enhance the body’s natural defense mechanisms against tumor cells and mitigate the side effects of conventional treatments.

Suggested use

If you use the extract regularly, take 1,000 – 2,000 mg daily. For using it as an antiviral agent, take 3,000 – 4,000 mg daily. For best results take the supplement on an empty stomach.


Organic Shiitake Mushroom Extract 20x Powder (Lentinus edodes). Concentrated 20x Extract made by distilled water extraction. Contains AHCC (Active Hexose Correlated Compound).


The various effects are not guaranteed and results may vary due to several factors between different people.

We strive to ensure the accuracy of the information provided by the manufacturers and recommend that you read all labels and warnings. However, the information is not a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment.

Weight (Bag)

1000g (35.3oz), 100g (3.5oz), 200g (7.1oz), 500g (17.6oz)


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Shopping Cart
Scroll to Top