Description

Organic Jiaogulan Extract Powder is an Asian plant with a wide range of potential health benefits. We also know the plant as Gynostemma Pentaphyllum and it is known to have powerful antioxidant and adaptogenic effects. Jiaogulan is actively being studied for its potential effects on the AMP-activated protein kinase (AMPK) pathway.

AMPK is an enzyme that plays a crucial role in regulating cellular energy balance, metabolism, and various physiological processes. The activation of the AMPK pathway stimulates glucose uptake, enhances mitochondrial function, and promotes energy expenditure. The positive metabolic effects relates to blood sugar regulation, lipid metabolism, and overall metabolic balance.

The anti-diabetic effect is possibly mediated by the activation of AMPK and the inhibition of PTP1B. Other effects appears to be from antioxidant enzymes that protects cells from oxidative damage over time.

Mitochondrial Function

Gynostemma activates the AMPK pathway for mitochondrial biogenesis, which is the process by which new mitochondria are formed in cells. Mitochondria are the cellular organelles responsible for generating ATP through oxidative phosphorylation. By increasing mitochondrial density and function, it supports cellular energy production and overall metabolic health.

Weight

Some people report weight loss when using gynostemma extract, which possibly is due to the effect of actiponin on metabolism and appetite regulation. Studies suggest that actiponin may promote the breakdown of fat stores and the utilization of stored fat for energy expenditure.

Anti-Inflammatory Antioxidant

Jiaogulan is rich in antioxidants, which helps to combat oxidative stress and reduce the risk for chronic disease. Antioxidants also support healthy aging and protect cells from damage. Oxidative stress in the body is associated with various chronic diseases, including arthritis and neuroinflammation.

Stress Reduction

Jiaogulan is classified as an adaptogen, which means it helps the body adapt to stressors and maintain homeostasis. Chronic stress accelerates aging by promoting oxidative damage, inflammation, and dysregulation of cellular processes. By contrast, the adaptogenic properties mitigates the detrimental effects of stress on cellular aging and support resilience against age-related stressors.

Energy and Stamina

Gynostemma extract may increase energy levels and physical endurance by several mechanisms. First by improving mitochondrial function, which are the powerhouses of cells responsible for generating energy in the form of adenosine triphosphate (ATP). Second, by improving oxygen delivery to tissues and enhancing cellular respiration it helps boost endurance and stamina during physical activity.

Heart

Jiaogulan links to several cardiovascular benefits, including the potential to lower blood pressure, reduce LDL cholesterol levels, and improve overall heart health. A key mechanism is that jiaogulan activates AMPK, which inhibits lipid synthesis and promotes fatty acid oxidation in the liver and skeletal muscle. This leads to reduced lipid accumulation and an improved lipid profile that contributes to cardiovascular health.

Aging

Jiaogulan contains various phytochemicals, including flavonoids, saponins, and polyphenols, which exhibit potent antioxidant properties. These compounds neutralizes harmful free radicals implicated in oxidative stress, cellular damage, inflammation, and DNA mutations. The herbal possesses anti-inflammatory properties that inhibits pro-inflammatory cytokines and signaling pathways. By reducing inflammation it helps to mitigate age-related inflammation and to promote overall health.

Antitumor Potential

Some studies suggest that gynostemma pentaphyllum may enhance immune function by increasing the activity of natural killer (NK) cells, T cells, and macrophages, which play crucial roles in identifying and destroying cancer cells. By enhancing immune surveillance, it may help the body recognize and eliminate cancerous cells. Studies also find that gynostemma induces apoptosis in various cancer cell lines that triggers their death and inhibits tumor growth. Lastly it inhibits angiogenesis, i.e. limits blood supply to tumors and impedes on their growth.

Suggested use

The suggested dose is 500 – 1000 mg a day.

Ingredients

Organic Jiaogulan Extract Powder (Gynostemma Pentaphyllum). Contains concentrated 20:1 extract.

Disclaimer

The various effects are not guaranteed and results may vary due to several factors between different people.

We strive to ensure the accuracy of the information provided by the manufacturers and recommend that you read all labels and warnings. However, the information is not a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment.