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Indole-3-Carbinol (I3C) 99% – Liver, Immune System, Anti-Tumor


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Premium Indole-3-Carbinol (I3C) is a dietary supplement made from glucosinolate glucobrassicin, which is a sulfur-containing compound found in cruciferous vegetables. I3C may help neutralize free radicals, the liver, and support breast health.

EAN: 0793869836797 SKU: 10005871 Categories: , , ,


Indole-3-Carbinol (I3C) 99% is a dietary supplement made from glucosinolate glucobrassicin, which is a sulfur-containing compound found in cruciferous vegetables, e.g. broccoli, cauliflower, and brussels sprouts. I3C is becoming increasingly popular as a nutraceutical, as it’s effective in neutralizing free radicals, detoxifying the liver, converting estrogen to the beneficial metabolite 2-hydroxyestrone, may help in maintaining health in reproductive organs and breasts, in supporting the immune system, and it maybe even in repress the growth of certain cancers.

Indole-3-carbinol (I3C) is converted into diindolylmethane (DIM) in the in the acid environment of the stomach. Similarly to the I3C it could help support , energy levels, joint function, mood, and cardiovascular health. DIM is intriguing because it similarly appears to help adjust estrogen levels and lowering the risk of tumors and diseases like lupus, which are linked to estrogen.


I3C exhibits anti-inflammatory properties, which can be beneficial in managing chronic inflammation. Chronic inflammation is linked to various health conditions, including cardiovascular disease, arthritis, and neurodegenerative disorders.


The antioxidant properties of indole-3-carbinol help neutralize free radicals in the body and support cellular health. Free radicals contribute to oxidative stress, which is implicated in aging and various chronic diseases.

Immune System

I3C’s influence on the immune system has been studied, and it may have immunomodulatory effects, which potentially enhances the body’s ability to defend against infections and diseases.

Skin Health

The impact on hormonal balance may extend to skin health. I3C may be beneficial for individuals with acne, particularly hormonal acne, as it addresses underlying factors related to hormone metabolism.


Preliminary research suggests that it may have cardiovascular benefits. I3C may help regulate lipid metabolism, contributing to a healthy lipid profile. Additionally, the anti-inflammatory and antioxidant effects may positively impact cardiovascular health.


I3C promotes the formation of metabolites, such as diindolylmethane (DIM), through the breakdown of estrogen. This helps modulate the metabolism and promotes the conversion of it into less potent forms. This balance is crucial for both men and women, as imbalanced levels can lead to various health issues.

Potentially Anti-Cancer

Research suggests that I3C may have potential cancer-preventive properties. It has been studied for its role in preventing female-related cancers, including breast, prostate, and ovarian cancers. The influence of I3C on estrogen metabolism may contribute to reducing the risk of certain malignancies.


Another mechanism is the increased apoptosis, or programmed cell death, of certain types of cells, including those with detrimental growth characteristics. By affecting the progression of the cell cycle, I3C may contribute to apoptosis in cells with abnormal growth characteristics.


I3C supports the body’s natural detoxification processes. It helps the liver metabolize and eliminate toxins, contributing to overall liver health. This detoxification support can be beneficial for individuals exposed to environmental pollutants.


I3C has been investigated for its potential benefits in weight management. It may influence factors related to metabolism and fat storage, making it of interest for individuals looking to support healthy weight.


The influence on estrogen metabolism may have implications for joint and bone health. It may contribute to maintaining bone density and supporting joint function, making it of interest for individuals with concerns related to osteoporosis or arthritis.


Some studies suggest that I3C may have neuroprotective effects, potentially benefiting brain health. It has been investigated for its role in reducing oxidative stress and inflammation in the brain, contributing to cognitive well-being.

Suggested use

The suggested dose is between 150 mg and 600 mg daily, which may be divided into two equal doses.


Indole-3-Carbinol (I3C) 99% Supplement. Contains no fillers.


The various effects are not guaranteed and results may vary due to several factors between different people.

We strive to ensure the accuracy of the information provided by the manufacturers and recommend that you read all labels and warnings. However, the information is not a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment.

Weight (Bag)

100g (3.5oz), 200g (7.1oz), 500g (17.6oz)


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